Product Pipeline and Funding
Global Health and Pandemic Preparedness
Supported almost exclusively by non-dilutive funding, Aldatu has received $16M from the National Institute of Allergy and Infectious Diseases [NIAID] to advance diagnostics using our PANDAA technology platform.
Product Pipeline and Funding
Global Health and Pandemic Prevention, Preparedness and Response
Supported almost exclusively by non-dilutive funding, Aldatu has received $16M from the National Institute of Allergy and Infectious Diseases [NIAID] to advance diagnostics using our PANDAA technology platform.
ReFocus I
$1.5M NIAID SBIR
Detects six drug resistance mutations (DRMs) in >99% of HIV-infected patients failing first-line antiretroviral treatment (ART).
Genotypes 24 patients in <2 hours.
Available as RUO product: aldatubio.com/product/pandaa-qdx-hivdr-rti/
ReFocus II
$3M NIAID SBIR
$3M NIAID Commercialization
Detects eight DRMs in HIV-infected patients failing protease inhibitor second-line antiretroviral treatment (ART). Genotypes 20 patients in <2 hours.
ExPAND
$3.3M NIAID Contract
Detects low-level DRM variants at 1% for all HIV antiretroviral drug classes.
ReFocus I
$1.5M NIAID SBIR
Detects six drug resistance mutations (DRMs) in >99% of HIV-infected patients failing first-line antiretroviral treatment (ART). Genotypes 24 patients in <20 hours.
Available as RUO product: aldatubio.com/product/pandaa-qdx-hivdr-rti/
ReFocus II
$3M NIAID SBIR
$3M NIAID Commercialization
Detects eight DRMs in HIV-infected patients failing protease inhibitor second-line antiretroviral treatment (ART). Genotypes 20 patients in <2 hours.
ExPAND
$3.3M NIAID Contract
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Detects low-level DRM variants at 1% for all HIV antiretroviral drug classes. |
Pandemic Preparedness
Viral Hemorrhagic Fevers
Pandemic Preparedness - Viral Hemorrhagic Fevers
The first pan-lineage real-time PCR assay for the qualitative detection of Lassa virus (LASV) RNA.
- The only assay for universal pan-lineage detection of the Lassa virus – detects all lineages of LASV with equal sensitivity.
- Fast – delivers accurate results from RNA in 1 hour
- One of the most sensitive LASV molecular diagnostics available, with a limit of detection 10 copies / reaction.
Available as an RUO product: aldatubio.com/product/pandaa-qdx-lasv
The first pan-lineage real-time PCR assay for the qualitative detection of Lassa virus (LASV) RNA.
- The only assay for universal pan-lineage detection of the Lassa virus – detects all lineages of LASV with equal sensitivity.
- Fast – delivers accurate results from RNA in 1 hour
- One of the most sensitive LASV molecular diagnostics available, with a limit of detection 10 copies / reaction.
Available as an RUO product: aldatubio.com/product/pandaa-qdx-lasv
The first universal, pan-clade CCHFV diagnostic.
- The first CCHFV diagnostic that meets the WHO R&D blueprint target product profile
- The only assay that can detect all CCHFV clades, and with equal sensitivity.
- Fast – delivers accurate results from RNA in 1 hour
- A limit of detection 10 copies / reaction.
Ebola and Marburg
$3M NIAID SBIR
Under development to detect all species of Ebolavirus and differentiation with Marburgvirus.
- Detect and differentiate Ebolavirus from Marburgvirus.
- Detect all six species of Ebolavirus with equal sensitivity.
Yellow fever
Under development to detect all genotypes of Yellow fever virus and differentiate from vaccine strains.
- A universal molecular diagnostic to detect all Yellow fever virus genotypes.
- Distinguishes infections caused by wild-type virus from adverse events arising from immunization with the Yellow fever live, attenuated vaccine.
The first universal, pan-clade CCHFV diagnostic.
- The first CCHFV diagnostic that meets the WHO R&D blueprint target product profile
- The only assay that can detect all CCHFV clades, and with equal sensitivity.
- Fast – delivers accurate results from RNA in 1 hour
- A limit of detection 10 copies / reaction.
Ebola and Marburg
$3M NIAID SBIR
Under development to detect all species of Ebolavirus and differentiation with Marburgvirus.
- Detect and differentiate Ebolavirus from Marburgvirus.
- Detect all six species of Ebolavirus with equal sensitivity.
Yellow fever
Under development to detect all genotypes of Yellow fever virus and differentiate from vaccine strains.
- A universal molecular diagnostic to detect all Yellow fever virus genotypes.
- Distinguishes infections caused by wild-type virus from adverse events arising from immunization with the Yellow fever live, attenuated vaccine.